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Recent Article Published: Magnetic nanoparticle-loaded electrospun poly(ε-caprolactone) nanofibers for drug delivery applications

Sunu1In this study, iron oxide (Fe 3 O 4) magnetic nanoparticles (MNPs) were loaded into poly (ε-
caprolactone)(PCL) nanofıber mats via electrospinning method and the composite materials
were characterized. MNPs were synthesized by a conventional co-precipitation method and
treated by oleic acid to obtain hydrophobic nanoparticles. The MNPs were added to PCL
solution before electrospinning at varying MNP feed concentrations (1: 25, 2: 25, 4: 25, 8: 25,
16: 25 and 32: 25; weight ratio of MNPs: polymer). The chemical structure of the nanofibrous
membranes was investigated by Fourier transform infrared spectroscopy (FTIR). Scanning
electron microscopy (SEM), and analyses by optical and confocal microscopes
demonstrated that MNP-loaded PCL nanofibers (MNP@ PCL NFs) were homogeneously
distributed in the membranes. Fiber diameter changed and bead formation occurred as …


Cite this article as:Demir, D., Güreş, D., Tecim, T. et al. Appl Nanosci (2018). https://doi.org/10.1007/s13204-018-0830-9